The mission of the Proteomics & Mass Spectrometry Facility at the Danforth Center is four-fold:

• Provide Danforth Center scientists with access to state-of-the-art instrumentation and technology with which to expand and attain their research endeavors
• Offer high-quality services in biomolecule separation, identification and structural analysis to internal and external clients
• Provide training to internal and external scientists interested in developing knowledge and skills in the areas of proteomics and mass spectrometry
• Produce first-rate publication quality results for all clients

The Proteomics & Mass Spectrometry Facility has processed thousands of service samples submitted from research laboratories located at the Danforth Center as well as from academic and commercial institutions worldwide. In addition, the facility has initiated research activities designed to expand analytic capabilities and has established collaborations with many principal investigators at various institutions. These activities have produced exciting results and publications, which are a testament to the facility's high standards and growing reputation.

With highly-specialized capabilities and research initiatives, the facility is well-prepared and positioned to serve as a regional, national and international resource in the fast developing fields of proteomics and metabolomics.  Browse our list of standard services, or contact us for consultation or method development.

If data from our instruments results in a publication, please cite us using the appropriate citation below.  Funding agencies require us to accurately report this data and it helps us in attracting and maintaining funding to provide top-class facilities.

6500 QTRAP Citation:  “This material is based upon work supported by the National Science Foundation under Grant No. DBI-1427621 for acquisition of the QTRAP LC-MS/MS.”
LTQ-Velos Pro Orbitrap Citation:  “This material is based upon work supported by the National Science Foundation under Grant No. DBI-0922879 for acquisition of the LTQ-Velos Pro Orbitrap LC-MS/MS.”
Orbitrap Fusion Lumos Citation:  “This material is based upon work supported by the National Science Foundation under Grant No. DBI-1827534 for acquisition of the Orbitrap Fusion Lumos LC-MS/MS.”

Data Retention Policy:

The Danforth Center Proteomics and Mass Spectrometry Facility will retain all raw and processed data for a 12-month period after data posting.  We encourage users to download their data and archive appropriately.  These data are included as .zip files in the Results page of your order.  There are a number of free, online data repositories that we recommend for archiving of mass spectrometry data.  These repositories accept data and will keep them as private archives until such time as the data are published or the depositor decides to make them public.  This publicly accessible archiving is in accordance with a number of scientific journals and is now widely accepted policy.  For proteomics datasets we recommend PRIDE or ProteomeXchange.  For small molecule datasets we recommend Metabolomics Workbench, MetaboLights or MetabolomeXchange.


PMSF Worldwide Impact

View PMSF Worldwide Impact in a larger map


Bradley Evans
Director, Proteomics & Mass Spectrometry

Danforth Center
975 N. Warson Rd.
St. Louis, MO 63132
(314) 587-1464



To schedule analysis of routine samples please contact us and then logon to our LIMS to place an order.

Link to Intranet Site (Internal Users Only)