39 North, a new innovation district, was announced on December 7, 2016.  The district includes 600 acres surrounding the Danforth Plant Science Center, BRDG Park, Helix Incubator, Yield Lab and Monsanto.  By connecting regional assets, improving mobility, creating development opportunities and additional greenspace will enhance the region’s ability to grow, attract and retain companies and top talent.


The 39 North Master Plan funded by a $500,000 grant from the U.S. Department of Commerce, presents a vision for  an innovation district in St. Louis County that is uniquely positioned to advance the region’s global leadership in plant and life sciences. The district will be geared toward lifestyle preferences often sought by highly-skilled employees, including mixed retail, residential and office space connected by walking and biking trails and green space. 

Community input was paramount to the process.  More than 45 meetings, focus group sessions and two community open houses were held to gather feedback from stakeholders including, scientists, residents, property owners and developers, elected officials, local businesses, the Missouri Water Company, the Missouri Department of Transportation and area educators for ideas to create a thriving district.

Five Transformative Goals 
  • Strengthen corridors and establish new traffic patterns
  • Connect assets and opportunity sites
  • Establish a cohesive development framework
  • Create a mixed-use center of activity
  • Communicate the district

In the near term, dedicated staff at the St. Louis Economic Development Partnership will manage implementation of the plan for 39 North in coordination with a steering committee of essential stakeholders, all of whom shaped the Master Plan. In the longer term, an empowered nonprofit entity will be created to ensure the continuation of the District’s mission.


Great Rivers Greenway awarded 39 North $400,000 to design an open space framework and biking and pedestrian paths that connect to the Centennial Greenway. Following a formal RFP process, the team assembled by Reitz & Jenz Engineering was selected the planning and design work is underway.

St. Louis County voted unanimously to approve $450,000 for preliminary planning for the redesign of Old Olive. The City of Creve Coeur provided an additional $50,000. This funding will support the development of a Great Streets plan to give Old Olive a localized, main-street look and feel, and improve mobility.  To lead the design, a team assembled by Christner Inc. was selected from the RFP process.

Funding for the redesign, engineering and construction of the Olive and Lindbergh Boulevard interchange was secured with $4 million from the Federal Highway Administration and a $1 million match from St. Louis County.  Following a formal RFP process, Access Engineering was selected to lead the project. Engineering began in Q3 2018, and construction is targeted for late 2019.

Venture Café @ 39 North gatherings are held from 4 PM to 7:30 PM on the third Tuesday of every month at the Danforth Plant Science Center.  The gatherings facilitate serendipitous collisions that drive creativity, foster collaboration and stimulate investment in innovation. The event is free and open to the public.


Read the strategic master plan in full
More Information