Pluton Biosciences Advances Development of Novel Bioinsecticides Through Participation in Wells Fargo Innovation Incubator

Pluton team collaborated with top Donald Danforth Plant Science Center researcher

St. Louis, MO, USA - September 24, 2021 - Pluton Biosciences is excited to announce that its participation in the Wells Fargo Innovation Incubator (IN2) program has generated a deeper understanding of how three novel bacteria work to kill disease-carrying mosquitoes.

Founded in 2017, Pluton Biosciences taps into the diverse world of microorganisms to develop eco-friendly products for carbon sequestration, agriculture, pharmaceuticals, biomaterials, and bioremediation. Pluton’s Micromining® Innovation Engine allows its scientists and engineers to discover microbes with novel activities in only a few months.

As a member of IN2’s seventh cohort, Pluton conducted research and development activities at the Donald Danforth Plant Science Center in St. Louis, as a program partner with the world’s largest independent plant science institute. Danforth’s biochemistry expertise has helped Pluton researchers unravel the chemistry behind three novel bioinsecticides discovered in 2017.

Pluton also received $250,000 in technical assistance with the opportunity for follow-on funding and access to the state-of-the-art expertise and resources from the Danforth Center, Wells Fargo, the U.S. Department of Energy’s National Renewable Energy Laboratory, and other IN2 partners. Companies selected for the program share a focus on developing technologies that support the agricultural sector while reducing environmental impact.

"The collaboration between the Danforth Center and Pluton has been an example of IN2 at its best, utilizing the strengths and expertise of our scientists and facilities to help an early-stage company validate an early technology and work through technical hurdles,” said Dr. Claire Kinlaw, Director of Innovation Commercialization at the Danforth Center. “In the case of Pluton, we were excited to help chemically characterize novel compounds derived from microbes. We are very pleased to have supported Pluton's creative entrepreneurial team.”

For the past year, Pluton has collaborated with Danforth Center Principal Investigator Dr. Toni Kutchan and researcher Dr. Santosh Kumar to understand the novel bacteria’s unique characteristics.

“Dr. Kutchan is a world expert in the chemical analysis of natural products. Our collaboration with Drs. Kutchan and Kumar allowed us to rapidly understand the chemical nature of our bioinsecticides and inform their development into next-generation products,” said Pluton Founder/Director of Research Ann Guggisberg, PhD. “We are grateful to have been selected to participate in the IN2 program and to work alongside such outstanding scientists.”

About the Donald Danforth Plant Science Center
Founded in 1998, the Donald Danforth Plant Science Center is a not-for-profit research institute with a mission to improve the human condition through plant science. Research, education and outreach aim to have impact at the nexus of food security and the environment, and position the St. Louis region as a world center for plant science. The Center’s work is funded through competitive grants from many sources, including the National Institutes of Health, U.S. Department of Energy, National Science Foundation, and the Bill & Melinda Gates Foundation. Follow us on Twitter at @DanforthCenter.  

About the Wells Fargo Innovation Incubator (IN2)
The Wells Fargo Innovation Incubator (IN2) is a $50 million technology incubator and platform funded by the Wells Fargo Foundation. Co-administered by and housed at the National Renewable Energy Laboratory (NREL) in Golden, Colorado, IN2’s mission is to speed the path to market for early-stage, clean-technology entrepreneurs. Launched in 2014 with an initial focus on supporting scalable solutions to reduce the energy impact of commercial buildings, IN2 has since expanded its focus to advance technologies that address the sustainable production of agriculture and housing affordability. For more information, visit

For additional information, contact: Karla Roeber, 314.406.4287