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Dr. Schnable's scientific investigations have been wide-ranging. Recently he was the co-lead author on the maize genome sequencing paper (Science) and a co-corresponding author on a Nature Genetics paper that
reported the re-sequencing of six additional maize haplotypes. Schnable serves as an associate editor for PLoS Genetics. In 2009 he was appointed a Chang Jiang Scholar Professor at China Agriculture University and in 2010 he was elected a fellow in the AAAS. He is also the managing partner for Data2Bio LLC which helps biologists design and analyze NGS projects.
He will discuss his project to generate a near-complete sequence of the maize inbred B73 utilized a minimal tiling path of approximately 16,000 mapped BAC clones. Project methodologies and outputs will be briefly reviewed before addressing genome-enabled investigations of genome structure and function.
In addition, Dr. Gloria Coruzzi, Carroll & Milton Petrie Professor, Center for Genomics and Systems Biology, and Chair, Department of Biology, New York University will be speaking Friday at the Fall Symposium.
Dr. Coruzzi research in plant systems biology combines genomic, bioinformatic, and system biology approaches to identify gene regulatory networks controlling nitrogen use efficiency and the evolution of seeds. Using machine-learning approaches, her lab has generated predictive regulatory networks, a hallmark of systems biology. These informatic tools are embodied in a systems-biology enabling software platform called VirtualPlant (http://www.virtualplant.org). This research, performed in collaboration with the NYU Courant Institute, is funded by the NIH, NSF and DOE.
Her topic will highlight plant systems biology: from predictive network modeling to trait evolution. The ultimate goal of systems biology is to predict how network states change under untested conditions or in response to modifications . Her first step towards this goal was the creation of an Arabidopsis multi-network where the “edges” connecting gene “nodes” are supported by metabolic, protein, RNA connections (http://www.virtualplant.org.)
To learn more about our 13th Annual Fall Symposium visit, http://www.danforthcenter.org/fall_symposium/. For the most up-to-date information, please follow us on Facebook & Twitter #FallSymposiumSTL.
| trait evolutionsystem biologySeedsPlant scienceplant genomicsNIHgenomeFall symposuimAgronomy