Oliver Yu

Dr. Yu got his B. Sc. from Department of Biophysics at the Fudan University in Shanghai, China, and Ph. D. from Department of Biology at the University of South Carolina, Columbia, SC. He did his postdoctoral training at the DuPont Company in Wilmington, Delaware. He joined the Donald Danforth Plant Science Center in 2001, serving as an Assistant Member, and later an Associate Member and Principal Investigator. He is currently an adjunct professor at the Department of Biology, Washington University in St Louis, and the Division of Plant Sciences at University of Missouri-Columbia.

RESEARCH | PUBLICATIONS | RESEARCH TEAM | LAB NEWS

Publications

Shi, C.Y., Yang, H., Wei, C.L., Yu, O., Zhang, Z.Z., Jiang, C.J., Sun, J., Li, Y.Y., Chen, Q., Xia, T., and Wan, X.C. (2011). Deep sequencing of the Camellia sinensis transcriptome revealed candidate genes for major metabolic pathways of tea-specific compounds. BMC Genomics 12, 131.
|PubMed | Request Copy |

Zhang, J., Wang, X., Yu, O., Tang, J., Gu, X., Wan, X., and Fang, C. (2010). Metabolic profiling of strawberry (Fragaria x ananassa Duch.) during fruit development and maturation. J Exp Bot, accepted
| Request Copy |

Yang, J., Chen, F., Yu, O., and Beachy, R. (2010). Controlled silencing of 4-Coumarate:Coenzyme A Ligase alters lignocellulose composition. Plant Physiol Biochem, accepted
| |Request Copy |

Wang, Y., Chen, H., and Yu, O. (2010). Metabolic engineering of resveratrol and other longevity boosting compounds. Biofactors accepted
|Request Copy |

Li, H., Deng, Y., Wu, T., Subramanian, S., and Yu, O. (2010). Mis-expression of miR482, miR1512, and miR1515 increases soybean nodulation. Plant Physiol, in press.
| PubMed | Request Copy |

Guttikonda, S.K., Trupti, J., Bisht, N., Chen, H., An, Y.C., Pandey, S., Xu, D., and Yu, O. (2010). Whole Genome Co-expression Analysis of Soybean Cytochrome P450 Genes Identified Nodulation-Specific P450 Monooxygenases. BMC Plant Biol, accepted

Gutierrez-Gonzalez, J.J., Wu, X., Gillman, J.D., Lee, J.D., Zhong, R., Yu, O., Shannon, G., Ellersieck, M., Nguyen, H.T., and Sleper, D.A. (2010). Intricate environment-modulated genetic networks control isoflavone accumulation in soybean seeds. BMC Plant Biol 10,
| PubMed | Request Copy |

Gutierrez-Gonzalez, J.J., Guttikonda, S.K., Tran, L.S., Aldrich, D.L., Zhong, R., Yu, O., Nguyen, H.T., and Sleper, D.A. (2010). Differential expression of isoflavone biosynthetic genes in soybean during water deficits. Plant Cell Physiol 51,936-948.
| PubMed | Request Copy |

Zhang, J., Subramanian, S., Stacey, G., and Yu, O. (2009). Flavones and flavonols play distinct critical roles during nodulation of Medicago truncatula by Sinorhizobium meliloti. Plant J 57, 171-183.
| PubMed | Request Copy |

Yu, O., and Wang, Y. (2009). The functions of flavonoids during legume-rhizobia interactions. In Ecological Aspects of Nitrogen Metabolism in Plants, J. Polacco and C. Todd, eds (accepted.)
| PubMed | Request Copy |

Yamaguchi, M., Valliyodan, B., Zhang, J., Lenoble, M.E., Yu, O., Rogers, E.E., Nguyen, H.T., and Sharp, R.E. (2009). Regulation of growth response to water stress in the soybean primary root. I. Proteomic analysis reveals region-specific regulation of phenylpropanoid metabolism and control of free iron in the elongation zone. Plant Cell Environ 33, 223-243.| PubMed | Request Copy |

Subramanian, S., Cho, U.H., Keyes, C., and Yu, O. (2009). Proteomic analysis of soybean xylem sap proteome in response to symbiotic and pathogenic microbe interactions. BMC Plant Biol 9, 119.
| PubMed | Request Copy |

Keyes, C.A., Subramanian, S., and Yu, O. (2009). Hairy root as a model system for undergraduate laboratory curriculum and research. Bioscene 35, 6-12.
| PubMed | Request Copy |

Gutierrez-Gonzalez, J.J., Wu, X., Zhang, J., Lee, J.D., Ellersieck, M., Shannon, J.G., Yu, O., Nguyen, H.T., and Sleper, D.A. (2009). Genetic control of soybean seed isoflavone content: importance of statistical model and epistasis in complex traits. Theor Appl Genet 119, 1069-1083.
| PubMed | Request Copy |

Cheng, H., Yu, O., and Yu, D. (2009). Polymorphisms of IFS1 and IFS2 genes are associated with isoflavone concentrations in soybean seeds. Plant Sci 175, 505-512
| Request Copy |

Zhang, J., and Yu, O. (2008). Metabolic engineering of isoflavone biosynthesis in seeds. In Modification of seed composition to promote health and nutrition, H. Krishnan, ed, pp. 151-177.
| Request Copy |

Yu, O., and Jez, J.M. (2008). Nature's assembly line: biosynthesis of simple phenylpropanoids and polyketides. Plant J 54, 750-762.
| PubMed | Request Copy |

Subramanian, S., Fu, Y., Sunkar, R., Barbazuk, W.B., Zhu, J.K., and Yu, O. (2008). Novel and nodulation-regulated microRNAs in soybean roots. BMC Genomics 9, 160.
| PubMed | Request Copy |

Schroeder, A.C., Kumaran, S., Hicks, L.M., Cahoon, R.E., Halls, C., Yu, O., and Jez, J.M. (2008). Contributions of conserved serine and tyrosine residues to catalysis, ligand binding, and cofactor processing in the active site of tyrosine ammonia lyase. Phytochemistry 69, 1496-1506.
| PubMed | Request Copy |

Li, L., He, H., Zhang, J., Wang, X., Bai, S., Stolc, V., Tongprasit, W., Young, N.D., Yu, O., and Deng, X.W. (2008). Transcriptional analysis of highly syntenic regions between Medicago truncatula and Glycine max using tiling microarrays. Genome Biol 9, R57.
| PubMed | Request Copy |

Halls, C., and Yu, O. (2008). Potential for metabolic engineering of resveratrol biosynthesis. Trends Biotechnol 26, 77-81.
| PubMed | Request Copy |

Graham, T.L., Graham, M.Y., and Yu, O. (2008). Genomics of secondary metabolism in soybean. In Genetics and Genomics of Soybean, G. Stacey, ed (New York: Springer), pp. 211-242.
| Request Copy |

Zhang, J., Subramanian, S., Zhang, Y., and Yu, O. (2007). Flavone synthases from Medicago truncatula are flavanone-2-hydroxylases and are important for nodulation. Plant Physiol 144, 741-751.
| PubMed | Request Copy |

Subramanian, S., Stacey, G., and Yu, O. (2007). Distinct, crucial roles of flavonoids during legume nodulation. Trends Plant Sci 12, 282-285.
| PubMed | Request Copy |

Graham, T.L., Graham, M.Y., Subramanian, S., and Yu, O. (2007). RNAi silencing of genes for elicitation or biosynthesis of 5-deoxyisoflavonoids suppresses race-specific resistance and hypersensitive cell death in Phytophthora sojae infected tissues. Plant Physiol 144, 728-740.
| PubMed | Request Copy |

Zhang, Y., Li, S.Z., Li, J., Pan, X., Cahoon, R.E., Jaworski, J.G., Wang, X., Jez, J.M., Chen, F., and Yu, O. (2006). Using unnatural protein fusions to engineer resveratrol biosynthesis in yeast and Mammalian cells. J Am Chem Soc 128, 13030-13031.
| PubMed | Request Copy |

Yu, O., Matsuno, M., and Subramanian, S. (2006). Flavonoids in flowers: Genetics and Biochemistry. In Floriculture, ornamental and plant biotechnology: Advances and topical issues J.A.T.d. Silva, ed (Global Science Books), pp. 283-293.
| Request Copy |

Yu, O. (2006). Metabolic engineering of the plant phenylpropanoid pathway. In Encyclopedia of Plant and Crop Science (London: Taylor & Francis.
| Request Copy |

Subramanian, S., Stacey, G., and Yu, O. (2006). Endogenous isoflavones are essential for the establishment of symbiosis between soybean and Bradyrhizobium japonicum. Plant J 48, 261-273.
| PubMed | Request Copy |

Ralston, L., and Yu, O. (2006). Metabolons involving plant cytochrome P450s. . Phytochemistry Review 5, 459-472
| Request Copy |

Chabaud, M., Boisson-Dernier, A., Zhang, J., Taylor, C.G., Yu, O., and Barker, D.G. (2006). Agrobacterium rhizogenes-mediated root transformation. In The Medicago truncatula handbook, U. Mathesius, ed.
| Open Access – Full | Request Copy |

Yu, O., and McGonigle, B. (2005). Metabolic engineering of isoflavone biosynthesis. Advances in Agronomy 86, 147-190
| Request Copy |

Subramanian, S., Graham, M.Y., Yu, O., and Graham, T.L. (2005). RNA interference of soybean isoflavone synthase genes leads to silencing in tissues distal to the transformation site and to enhanced susceptibility to Phytophthora sojae. Plant Physiol 137, 1345-1353.
| PubMed | Request Copy |

Ralston, L., Subramanian, S., Matsuno, M., and Yu, O. (2005). Partial reconstruction of flavonoid and isoflavonoid biosynthesis in yeast using soybean type I and type II chalcone isomerases. Plant Physiol 137, 1375-1388.
| PubMed | Request Copy |

Subramanian, S., Xu, L., Lu, G., Odell, J., and Yu, O. (2004). The promoters of the isoflavone synthase genes respond differentially to nodulation and defense signals in transgenic soybean roots. Plant Mol Biol 54, 623-639
| Request Copy |

Subramanian, S., Hu, X., Lu, G., Odelland, J.T., and Yu, O. (2004). The promoters of two isoflavone synthase genes respond differentially to nodulation and defense signals in transgenic soybean roots. Plant Mol Biol 54, 623-639.
| PubMed | Request Copy |

Bennett, J.O., Yu, O., Heatherly, L.G., and Krishnan, H.B. (2004). Accumulation of genistein and daidzein, soybean isoflavones implicated in promoting human health, is significantly elevated by irrigation. J Agric Food Chem 52, 7574-7579.
| PubMed | Request Copy |

Yu, O., Shi, J., Hession, A.O., Maxwell, C.A., McGonigle, B., and Odell, J.T. (2003). Metabolic engineering to increase isoflavone biosynthesis in soybean seed. Phytochemistry 63, 753-763.
| PubMed | Request Copy |

Yu, O., Jung, W., Shi, J., Croes, R.A., Fader, G.M., McGonigle, B., and Odell, J.T. (2000). Production of the isoflavones genistein and daidzein in non-legume dicot and monocot tissues. Plant Physiol 124, 781-794.
| PubMed | Open Access – Full | Open Access – Abstract | Request Copy |

Jung, W., Yu, O., Lau, S.M., O'Keefe, D.P., Odell, J., Fader, G., and McGonigle, B. (2000). Identification and expression of isoflavone synthase, the key enzyme for biosynthesis of isoflavones in legumes. Nat Biotechnol 18, 208-212.
| PubMed | Open Access – Full | Open Access – Abstract | Request Copy |

Yu, X., Sukumaran, S., and Mrton, L. (1998). Differential expression of the arabidopsis nia1 and nia2 genes. cytokinin-induced nitrate reductase activity is correlated with increased nia1 transcription and mrna levels. Plant Physiol 116, 1091-1096.
| PubMed | Request Copy |

Czako, M., Wilson, J., Yu, X., Marton, L. (1993). Sustained root culture for generation and vegetative propagation of transgenic Arabidopsis thaliana. Plant Cell Rep 12, 603-606
| Request Copy