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| Selected Publications |
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Mishra, G, W. Zhang, F. Deng,
J. Zhao, and X. Wang. 2006. A bifurcating pathway directs
abscisic acid effects on stomatal closure and opening in
Arabidopsis. Science 312: 264-266 |
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Li, M., C. Qin, R. Welti., and
X. Wang. 2006. Double knockouts of phospholipase Dζ1 and ζ2
in Arabidopsis affect root elongation during
phosphate-limited growth, but do not affect root hair
patterning. Plant Physiol. 140: 761-770 |
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Wang, X., W. Li., M. Li., and
R. Welti. 2006. Profiling lipid changes in plant response to
low temperatures. Physiol. Plant. 126:90-96 |
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Wang, X. 2006. Phospholipid-derived
signaling in plant response to temperature and water
stresses. Genetic Engineering, 27: 57-66 |
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Wang, X., S.D. Devaiah, W.
Zhang, and R. Welti. 2006. Signaling functions of
phosphatidic acid. Prog. Lipid Research (in press) |
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Zhang W., Yu L., Zhang Y. and
X. Wang. 2005. Phospholipase D in the signaling network of
plant responses to abscisic acid and reactive oxygen
species. Biochim. Biophys. Acta 1736:1-9 |
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Wang, X. 2005. Regulatory
functions of phospholipase D and phosphatidic acid in plant
growth development, and stress responses. Plant Physiol.
139:566-573 |
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Welti, R., J. Shah, S. LeVine,
W. Esch, T. Williams, and X. Wang. 2005. High throughput
lipid profiling to identify and characterize genes involved
in lipid metabolism, signaling, and stress response. In
Functional Lipidomics. Edited by L. Feng and G.
Prestwich, CRC Press , Boca Raton, FL. pp. 308-320 |
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Zhang, W., C. Qin, J. Zhao, and X. Wang 2004. Phospholipase Da1-derived phosphatidic acid interacts with ABI1 phosphatase 2C and regulates abscisic acid signaling. Proc. Natl. Acad. Sci. USA 101: 9508-9513 |
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Li, W., M. Li, W. Zhang, R. Welti, and X. Wang. 2004. The plasma membrane-bound phospholipase Dd enhances freezing tolerance in Arabidopsis. Nature Biotech. 22: 427-433.
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Zhao, J. and X. Wang. 2004. Arabidopsis phospholipase Dα1 interacts with the heterotrimeric G-protein a-subunit through a motif analogous to the DRY motif in G-protein-coupled receptors. J. Biol. Chem. 279:1794-1800. |
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Pappan, K, L. Zheng, R. Krishnamoorthi, and X. Wang 2004. Evidence for and characterization of Ca2+ binding to the catalytic region of Arabidopsis phospholipase Dß. J. Biol. Chem.
279: 47833-47839 |
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Wang, X. 2004. Lipid signaling. Curr. Opin. Plant Biol. 7: 329-336. |
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Welti, R and X. Wang. 2004. Lipid species profiling: A high throughput approach to identify lipid compositional changes and determine the function of genes involved in lipid metabolism and signaling. Curr. Opin. Plant Biol. 7: 337-344. |
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Zhang W., C. Wang, C. Qin, T. Wood, G. Olafsdottir, and X. Wang. 2003. Phospholipase Dd and phosphatidic acid decrease H2O2-induced cell death in Arabidopsis. Plant Cell 15: 2285-2295. |
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McGee J.D., J. Roe, T.A. Sweat, X. Wang, J.A. Guikema, and J.E. Leach. 2003. Rice phospholipase D isoforms show differential cellular location and gene induction. Plant Cell Physiol. 44: 1013-1026. |
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Welti R and X. Wang 2003. Lipidomics. Inform 14: 607-608. |
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Welti, R., X. Wang, and T.D. Williams. 2003. Electrospray ionization tandem mass spectrometry scan modes for plant chloroplast lipids. Anal. Biochem. 314: 149-152. |
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Kusner, D.J., J.A. Barton, C. Qin, X. Wang, S.S. Iyer. 2003. Evolutionary conservation of physical and functional interactions between phospholipase D and actin. Arch. Biochem. Biophys. 412: 231-241. |
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Qin, C, W. Li, Y. Hong, W. Zhang, T. Wood, M. Li, R. Welti, and X. Wang 2003. Two novel types of Arabidopsis phospholipase D: oleate-stimulated PLDd and Ca2+-independent PLDz1. Advanced Research on Plant Lipids, ed. N. Murata, M Yamada, I. Nishida, H. Okuyama. J. Sekiya, and W. Hajime. Kluwer Academic Publishers, Dordrecht/Boston/London. pp. 259-262. |
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Wang, X. 2002. Phospholipase D in hormonal and stress signaling. Current Opinion Plant Biol. 5: 408-414. |
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Qin, B, C. Wang, and X. Wang. 2002. Kinetic analysis of Arabidopsis phospholipase Dd: substrate preference and mechanism of activation by calcium and phosphatidylinositol 4,5-bisphosphate. J. Biol. Chem. 277: 49685-49690. |
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Kusner D.J., J.A. Barton, K-K. Wen, X. Wang, P.A. Rubenstein, and S.S. Iyer. 2002. Regulation of phospholipase D activity by actin: I actin exerts bidirectional modulation of mammalian PLD activity in a polymerization-dependent, isoform-specific manner. J. Biol. Chem. 277: 50683-50692. |
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Welti, R., W. Li, M. Li, Y. Sang, H. Biesiada, H-E. Zhou, C.B. Rajashekar, T.D. Williams, and X. Wang. 2002. Profiling membrane lipids in plant stress responses: role of phospholipase Da in freezing-induced lipid changes in Arabidopsis. J. Biol. Chem. 277: 31994-32002. |
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Zheng, L., J. Shan, R. Krishnamoorthi, and X. Wang. 2002. Activation of plant phospholipase Db by phosphatidylinositol 4,5-bisphosphate: characterization of binding site and mode of action. Biochemistry 41: 4546-4553. |
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Wang, X. C. Wang, Y. Sang, C. Qin, and R. Welti. 2002. Networking of phospholipases in plant signal transduction. Physiol. Plant. 128: 1057-1068. |
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Qin, C. and X. Wang. 2002. The Arabidopsis phospholipase D family: characterization of a Ca2+-independent and phosphatidylcholine-selective PLDz1 with distinct regulatory domains. Plant Physiol. 128: 1057-1068. |
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Wang, X. Plant Phospholipases. 2001. Annu. Rev. Plant Physiol. Plant Mol. Biol. 52:211-231 |
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Sang, Y., S. Zheng, W. Li, B. Huang, and X. Wang. 2001. Regulation of plant water loss by manipulating the expression of phospholipase Da. Plant J. 28:135-144. |
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Wang, C. and X. Wang. 2001. A novel phospholipase D of Arabidopsis that is activated by oleic acid and associated with the plasma membrane. Plant Physiol. 127: 1102-1112. |
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Sang, Y., D. Cui, and X. Wang. 2001. Phospholipase D- and phosphatidic acid-mediated generation of superoxide in Arabidopsis. Plant Physiol. 126: 1449-1458. |
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Zien, C.A., C. Wang, X. Wang, and R. Welti. 2001. In-vivo substrates and the contribution of the common phospholipase D, PLDa, to wound-induced metabolism of lipids in Arabidopsis. Biochim. Biophys. Acta. 1530: 236-248. |
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Wang, C., C. Zien, M. Afitlhile, R. Welti, D.F. Hildebrand, and X. Wang. 2000. Involvement of phospholipase D in wound-induced accumulation of jasmonic acid in Arabidopsis. Plant Cell 12: 2237-2246. |
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Zheng, L., R. Krishnamoorthi, M. Zolkiewski, and X. Wang. 2000. Distinct calcium binding properties of novel C2 domains of plant phospholipase Da and
b. J. Biol. Chem. 275:19700-19706. |
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Ransom-Hodgkins, W.D., I. Brglez, X. Wang, W.F. Boss. 2000. Calcium-induced proteolysis of eEF1A. Plant Physiol. 122: 957-965. |
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Zhang, W. and X. Wang. 2000. Phospholipid metabolism and signal transduction in plants. Chinese Bulletin of Life Sciences 12:100-104. |
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Wang, X. 2000. Multiple forms of phospholipase D in plants: the gene family, catalytic and regulatory properties, and cellular functions. Progress in Lipid Research 39:109-149. |
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Wang, X., C. Wang, Y. Sang, L. Zheng, and C. Qin. 2000. Determining functions of multiple phospholipase Ds in stress response in Arabidopsis. Bioch. Soc. Trans. 28: 813-816. |
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Leach, J.E., L. Lloyd, D. McGee, X. Wang, and J.A. Guikema. 2000. Trafficking of plant defense response compounds. In N.T. Keen, S. Mayama, J.E. Leach, and S. Tsuyumu eds: Delivery and Perception of Pathogen Signals in Plants. APS Press, Minneapolis, MN. pp. 241-250. |
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Lu, F., S. Zheng, and X. Wang. 1999. Subcellular distribution and tissue expression of phospholipase Da,
b, and
g in Arabidopsis. Plant Physiol. 119:1371-1378. |
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Wang, X. 1999. The role of phospholipase D in signaling cascades. Plant Physiol. 120: 645-651. |
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Pappan, K and X. Wang. 1999. Plant phospholipase Da is an acidic phospholipase active at near-physiological Ca2+ concentrations. Arch. Biochem. Biophys. 368: 347-353. |
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Pappan, K. and X. Wang. 1999. Molecular and biochemical properties and physiological roles of plant phospholipase D. Biochim. Biophys. Acta 1439: 151-166. |
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Qin, W., J.H. Dyer, L. Zheng, and X. Wang. 1999. Isolation and nucleotide sequence of the fourth phospholipase D (accession No. AF138281), PLDg2, from Arabidopsis thaliana. Plant Physiol. 120:635. |
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Pappan, K., S. Austin-Brown, K. Chapman and X. Wang. 1998. Substrate selectivities and lipid modulation of phospholipase Da,
b, and
g from plants. Arch. Biochem. Biophys.353:131-140. |
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Ryu, S.B. and X. Wang. 1998. Increase in free linolenic and linoleic acids associated with phospholipase D-mediated hydrolysis of phospholipids in wounded castor bean leaves. Biochim. Biophys. Acta 1393:193-202.
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Wang, X., K. Pappan, L. Fan, and W. Qin. 1998. Multiple forms of phospholipase D in plant hormonal and stress signaling. In J. Sanchez et al. Eds: Advances in Plant Lipid Research. Servicio de Publicaciones, Spain. pp 398-401. |
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Pappan, K. and X. Wang. 1998. Regulation of plant phospholipase D by polyphosphoinositides and non-lamellar lipids. In J. Sanchez et al. Eds: Advances in Plant Lipid Research. Servicio de Publicaciones, Spain. pp 402-405. |
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Lu, F., S. Zheng, and X. Wang. 1997. Antisense suppression of phospholipase Da retards abscisic acid- and ethylene- promoted senescence in postharvest Arabidopsis leaves. Plant Cell. 9:2183-2196. |
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Pappan, K. S. Zheng, and X. Wang. 1997. Identification and characterization of a novel phospholipase D that requires polyphosphoinositides and submicromolar calcium for activity in Arabidopsis. J. Biol. Chem. 272:7048-7054. |
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Pappan, K. W. Qin, J.H. Dyer, L. Zheng, and X. Wang. 1997. Molecular cloning and functional analysis of polyphosphoinositide-dependent phospholipase D, PLDb, from Arabidopsis. J. Biol. Chem. 272:7055-7061. |
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Qin, W., K. Pappan, and X. Wang.1997. Molecular heterogeneity of PLD: cloning of plant PLDg and regulation of PLDg,
b, and
a by polyphosphoinositides and Ca2+. J. Biol. Chem. 272:28267-28273. |
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Wang, X., S. Zheng, K. Pappan, and L. Zheng. 1997. Characterization of phospholipase D-overexpressed and suppressed transgenic tobacco and Arabidopsis. in J.P. Williams, M.U. Khan, N.W. Lem eds: Physiology, Biochemistry and Molecular Biology of Plant Lipids. Kluwer Academic Publishers, Boston, pp. 345-347. |
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Xu, L., S. Zheng, L. Zheng, and X. Wang. 1997. Promoter analysis and expression of a phospholipase D gene from Ricinus communis L. Plant Physiol. 115:387-395. |
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Wang, X. 1997. Molecular analysis of phospholipase D. Trend. Plant Sci. 2:261-266. |
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Young, S.A., X. Wang, and J.E. Leach. 1996. Changes in the plasma membrane distribution of rice phospholipase D during resistant interaction with Xanthomonas oryzae pv oryzae. Plant Cell 8:1079-1090. |
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Xu, L., A.Q. Paulsen, S.B. Ryu, and X. Wang. 1996. Intracellular localization of phospholipase D in leaves and seedling tissues of castor bean. Plant Physiol. 111:1001-107. |
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Xu, L., L. Zheng, S.J. Coughlan, and X. Wang. 1996. Structure and analysis of phospholipase D gene from Ricinus communis L. Plant Mol. Biol. 32:767-771.
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Ryu, S.B. and X. Wang. 1996. Activation of phospholipase D and the possible mechanism of activation in wound-induced lipid hydrolysis in castor bean leaves. Biochim. Biophys. Acta 1303:243-250. |
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Ryu, S.B., L. Zheng, and X. Wang. 1996. Changes in phospholipase D expression in soybeans during seed development and following germination. J. Am. Oil Chem. Soc. 73:1171-1176. |
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Dyer, J.H., S. Zheng, and X. Wang. 1996. Structural heterogeneity of phospholipase D in ten dicots. Biochem. Biophys. Res. Commu. 221:31-36. |
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Ryu, S.B. and X. Wang. 1995. Expression of phospholipase D during castor bean leaf senescence. Plant Physiol. 108:713-719. |
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Dyer, J.H., L. Zheng, and X. Wang. 1995. Cloning and nucleotide sequence of a cDNA encoding phospholipase D from Arabidopsis (Accession No. U36381) (PGR 95-096). Plant Physiol. 109:1497. |
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Wang, X., L. Xu, and L. Zheng. 1994. Cloning and expression of phosphatidylcholine-hydrolyzing phospholipase D from Ricinus communis L. J. Biol. Chem. 269:20312-20317. |
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Dyer, J.H., S.B. Ryu, and X. Wang. 1994. Multiple forms of phospholipase D following seed germination and during leave development of castor bean. Plant Physiol. 105:715-724. |
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Wang, X. 1993. Phospholipases. in T.S. Moore ed: Lipid Metabolism In Plants. CRC Press, Boca Raton, FL, pp. 499-520. |
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Wang, X., J.H. Dyer, and L. Zheng. 1993. Purification and immunological analysis of phospholipase D from germinating castor bean endosperm. Arch. Biochem. Biophys. 306: 486-494. |
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Zheng, L., X. Wang, and H. D. Braymer. 1992. Purification and N-terminal sequences of two polypeptides encoded by mcrB from Escherichia coli K-12. Gene. 112:97-100. |
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Wang, X. and T.S. Moore, Jr. 1991. Phosphatidylethanolamine biosynthesis in castor bean endosperm: Intracellular distribution and characteristics of CTP:ethanolamine-phosphate cytidylyltransferase. J. Biol. Chem. 266:19981-19987. |
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Wang, X. and T.S. Moore, Jr. 1990. Phosphatidylcholine biosynthesis in castor bean endosperm: purification and properties of CTP:choline-phosphate cytidylyltransferase. Plant Physiol. 93:250-255. |
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Moore, Jr., T.S. and X. Wang. 1990. A comparison of CTP:cholinephosphate cytidylyltransferase and CTP:ethanolaminephosphate cytidylyltransferase of castor bean endosperm. In P.J. Quinn and J.L. Harwood Eds: Plant Lipid Biochemistry, Structure, and Utilization. Portland Press, pp.251-253. |
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Wang, X. and T.S. Moore, Jr. 1989. Partial purification and characterization of CTP:choline-phosphate cytidylyltransferase from castor bean. Arch. Biochem. Biophys. 274:388-347. |
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Wang, X., H.A. Norman, J.B. St. John, T. Yin, and D.F. Hildebrand. 1989. Comparison of fatty acid composition in soybean tissues with low linolenate mutants. Phytochem. 28:411-414. |
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Wang, X., G.Bookjans, M. Altschuler, G.B. Collins, and D.F. Hildebrand. 1988. Alteration of the synthesis of lipoxygenase in the early stages of soybean cotyledon culture. Physiol. Plant. 72:127-132. |
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Wang, X. and D.F. Hildebrand. 1987. Effect of a substituted pyridazinone on the decrease of lipoxygenase activity in soybean cotyledons. Plant Science. 51:29-36. |
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Wang, X. D.F. Hildebrand, H.A. Norman, M.L. Dahmer, J.B. St. John, and G.B. Collins. 1987. Reduction of linolenate content in soybean cotyledons by a substituted pyridazinone. Phytochem. 26:955-960. |
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Wang, X., D.F. Hildebrand, and G.B. Collins. 1987. Identification of proteins associated with the change in linolenate content of soybean cotyledons. In P. K. Stumpf, J. B. Mudd, and W. D. Nes Eds: The metabolism, Structure, and Function of Plant Lipids. Plenum Press, pp.533-535. |
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Hildebrand, D.F., M. Altschuler, G. Bookjans, G. Benzion, T.R. Hamilton-Kemp, R. A. Anderson, J.G. Rodriguez, J.C. Polacco, M.L. Dahmer, A.G. Hunt, X. Wang, and G.B. Collins. 1987. Physiological and transformational analysis of lipoxygenase. |
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In P.K. Stumpf, J.B. Mudd, and W.D. Nes Eds: The metabolism, Structure, and Function of Plant Lipids. Plenum Press, pp. 715-717. |
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Wang, X., K.A. Feldmann, and R.L. Scholl. 1988. A chlorate-hypersensitive, high nitrate/chlorate uptake mutant of Arabidopsis thaliana. Physiol. Plant. 73:305-310.
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Wang, X., R.L. Scholl, and K.A. Feldmann. 1986. Characterization of a chlorate-hypersensitive, high nitrate reductase Arabidopsis thaliana mutant. Theor. Appl. Genet. 72:328-336. |
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